The recent definition of recurrent miscarriages is TWO consecutive miscarriages in contrast to the previous definition of THREE consecutive miscarriages. The reason for this simple – it was previously thought that the cause for three consecutive miscarriages was different than that of two, but this has now been shown to be not true. Hence clinicians should start investigating patients after the loss of two pregnancies.
Anti-phospholipid antibody syndrome (APLA syndrome) has been shown to be a cause and a recent study (2009) published from University Malaya showed that the presence of these strange antibodies is actually not that uncommon in Malaysia!
All women with recurrent miscarriages should be started on Low molecular weight heparin and low dose aspirin (RCOG Guidelines 2011).